If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4-trichloro-benzene is a colorless liquid. This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Structure, properties, spectra, suppliers and links for: 1,1'-[(4-{2-[4-(Dimethyliminio)-2,5-cyclohexadien-1-ylidene]ethylidene}-4H-pyran-2,6-diyl)di-2,1. The EPA has stated that 1,2,4-trichlorobenzene is not classifiable as to human carcinogenicity. From: Modern Inorganic Synthetic Chemistry, 2011 Related terms: Aqueous Solution View all Topics Download as PDF About this page Trichlorobenzenes Increased adrenal weights; vacuolization of zona fasciculata in the cortex. Res. Huaxue Xuebao, 1987, 45, 1184-1187. It is virtually the exclusive product from the chlorination of 1,4-dichlorobenzene. K. See also. Medium. form is 1,2,4-Trichlorobenzene, Last Updated Date : HTML 5 canvas support. Articles of 1,2,4-Trichlorobenzene are included as well. Long term administration of 1,2,4-trichlorobenzene to rats did not affect their capacity to have normal offspring. Price (EUR) Price: 98,60. [all data], Schlosser, Marzi, et al., 2001 #=0!w}S&!T7U/9s$5U]O~K%~ed>7ueY?*us6/Wn]/LfSG{q&^{Wz;Ec' SUvE9d"Mxx*?~:YfDK(@+hwh'3hbc^.P)d!9(@ !pqp888 j"Si)rZr Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Aim, Karel, [all data], Ruscic, Klasinc, et al., 1981 Determination of the standard enthalpies of formation of polychlorobenzenes. How can families reduce their risk for exposure to trichlorobenzenes? HeH + has bond order 1.. d(ln(kH))/d(1/T) = Temperature dependence constant (K), Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: P264: Wash skin thoroughly after handling. Pioneering excellence with Steritest Symbio Pumps. Sears, G.W. [all data], Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References. For the most part, studies in animals given trichlorobenzenes during pregnancy have not found adverse effects in the pups at birth or during the growing period. Trichlorobenzenes have been used as solvents. . Please enable JavaScript and reload this page. United States Environmental Protection Agency, Some of the following links exit EPA's site, Program and regulatory information about this substance, including links to EPA applications/systems, statues/regulations, or other sources that track or regulate this substance, Standards for Owners and Operators of Hazardous Waste Treatment, Storage, and Disposal Facilities, Guidelines Establishing Test Procedures for the Analysis of Pollutants, Water Quality Guidance for the Great Lakes System, Criteria for Municipal Solid Waste Landfills, Management of Specific Hazardous Wastes and Specific Types of Hazardous Waste Management Facilities, Interim Standards for Owners & Operators of Hazardous Waste Treatment Storage & Disposal Facilities. NIST subscription sites provide data under the J. Chem. for GPC of polyolefines such as PE or PP which are otherwise insoluble. Stull, Daniel R., Chemical Structure. We take your privacy seriously. Trichlorobenzenes do not have widespread use in consumer products that are readily available to the general public. Select a region with data to zoom. J., 2001, 7, 16, 3511-3516, https://doi.org/10.1002/1521-3765(20010817)7:16<3511::AID-CHEM3511>3.0.CO;2-U 2-Bromo-1,3,4-trichlorobenzene (TRC) data available from this site, much more physical m[#&Pk.21af%2HMG).&*Y:-]"iz_07c,~:W\xrGZMYiH+$v1iGkM'K'&^Qirv9rw(}79s>mBo7O M Future versions of this site may rely on 238,252,276,284-286 The lower viscosity of the reaction mixture allowed for the better control of the process. van de Lande, L.M.F., It is unlikely that the general public will be exposed to high amounts of trichlorobenzenes. Thank you for taking the time to confirm your preferences. Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Polednicek, Milos; Aim, Karel; Jose, Jacques; Zbransk, Milan, Maintain clean baselines and improve chromatography run reproducibility with efficient filtration. Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. Based on data from 279. Measurements of Saturated Vapor Pressure above the Liquid Phase for Isomeric Dichlorobenzenes and 1,2,4-Trichlorobenzene, Chemical Structure for 1,2,4-Trichlorobenzene. See EPAs PDF page to learn more. Measurements of (dV/dT)p, (dV/dP)T, and (dH/dT)p by flux calorimetry, Trichlorobenzene (TCB) may refer to any of three isomeric chlorinated derivatives of benzene with the molecular formula C6H3Cl3. This table shows how each list refers to the substance. Data, 1998, 43, 5, 770-775, https://doi.org/10.1021/je9701442 Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, kH(T) = kH exp(d(ln(kH))/d(1/T) ((1/T) - 1/(298.15 K))) endstream endobj 27 0 obj <>stream reaction search for this species. 1,2,4-Trichlorobenzene 98.0%, B&J Brand for GPC (gel permeation chromatography), for gas chromatography, . Follow the links above to find out more about the data These clinics specialize in recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. click the mouse on the plot to revert to the orginal display. Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt. Institute of Standards and Technology, nor is it intended to imply The isomers may also have different chemical and . Total Toxic Organics (TTO) Effluent Guidelines Part 413.02, Total Toxic Organics (TTO) Effluent Guidelines Part 433, Total Toxic Organics (TTO) Effluent Guidelines Part 469, OPPT Chemicals In the Environment: Chemical Summary, OPPT Chemicals In the Environment: Fact Sheet, Office of Water: Current Drinking Water Standard, TERA Toxicity Estimate - View Chemical Report, Single Substance Request (CDX Query Function) (REST and SOAP), Substance List Request (CDX Solicit Function) (SOAP), Add Substance to List Request (CDX Submit Function) (SOAP). Standard Reference Data Act. jcamp-plot.js. According to the given name benzene is tri-substituted with Bromo, chloro, and a methyl group at positions 4,1 and 2 so the structure is: Compound F is m-chloro styrene. Selling Leads | It is not known whether trichlorobenzenes could affect reproduction in humans. In soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be immobile based upon an estimated Koc of 9.3X10+4. Not assessed under the IRIS Program. 1,2,4-trichlorobenzene Hexachlorobenzene 1,2-dichloroethane 1,1,1-trichloroethane Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane However, this was based on studies conducted prior to 1990; newer information has not been evaluated. Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) 1,2,4-Trichlorobenzene for synthesis. 15, Am. If you have questions or concerns, please contact your community or state health or environmental quality department or: For more information, contact: Acta, 1986, 105, 101-110. This substance exists as a Related Substance of the following substances. However, NIST makes no warranties to that effect, and NIST Thermochim. such sites. Find the products and services for your process. Mice given 1,2,4-trichlorobenzene in the food for 2 years developed cancer of the liver. All references to Merck refer to Merck KGaA, Darmstadt, Germany. Yan, H.; Gu, J.; An, X.; Hu, R., This ToxFAQsTM information is taken from the 2014 Toxicological Profile for Trichlorobenzenes produced by the Agency for Toxic Substances and Disease Registry, Public Health Service, U.S. Department of Health and Human Services in Atlanta, GA. This page allows searching It is a derivative of benzene with three chloride substituents. . Eng. Chamblee, GA 30341-3717 QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES. The Action of Sodium Methylate on SOme Derivatives of m-Dichlorobenzene, errors or omissions in the Database. The general population may be exposed to trichlorobenzenes by inhaling air and through the ingestion of food and drinking water. Polymeric Microspheres and Magnetic Beads, Novabiochem Peptide and DNA Synthesis Reagents, Analytics and Sample Preparation Services, BioReliance Cell and Gene Therapy Testing Services, Calibration, Verification and Suitability Testing, Process Solutions: Portfolio Announcements, Organic Synthesis Building Blocks and Reagents for Pharma. Physical Properties of Chemical Compounds, Advances in Chemistry Series No. Cookies used to make website functionality more relevant to you. How can trichlorobenzenes affect my health? spectrum (can be printed in landscape orientation). Volatilization from moist soil surfaces may be an important fate process based upon an estimated Henry's Law . P264: Wash skin thoroughly after handling. by the U.S. Secretary of Commerce on behalf of the U.S.A. Process wastes from the production of certain chlorinated aliphatic hydrocarbons by free radical catalyzed processes, as defined. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. [all data], Platonov and Simulin, 1985 Understanding Solidification of Polythiophene Thin Films during Spin-Coating: Effects of Spin-Coating Time and Processing Additives. Merck KGaA, Darmstadt, Germany, 2014. The purpose of the fee is to recover costs associated available from the NIST/EPA/NIH Mass Spectral Library. Physical Properties. Combustible. Platonov, V.A. The acidity of chloro-substituted benzenes: A comparison of gas phase, ab initio, and kinetic data, J., 1958, 69, 181. All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details. CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. - 298. There are no studies of cancer in people exposed to trichlorobenzenes. Follow the links above to find out more about the data Trichlorobenzenes have been identified in a variety of food items including vegetables, milk, eggs/meat, and oils produced from various nuts and seeds. Colorless liquid or crystalline solid (below 63F) with an aromatic odor. ; 1.) Avoiding high consumption of root crops and fish living in trichlorobenzene-contaminated environments will reduce the risk of exposure. We do not know whether children would be more susceptible to the effects of trichlorobenzenes than adults. It appears that your browser has JavaScript disabled. How can trichlorobenzenes affect children? Database and to verify that the data contained therein have Greater control & increased flexibility for both small & large molecule development & manufacturing processes. Biochem. Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) The lower energy states of HeH + is reached when product formed are He + H +.. Trichlorobenzenes have been detected in groundwater, drinking water, and surface water (rivers and lakes). Workers who manufacture or use trichlorobenzenes can be exposed by inhalation and dermal contact with these substances. Chem. Vapor Pressures of the Isomeric Trichlorobenzenes in the Low Pressure Region, 1,2,4-trichlorobenzene EC Number: 204-428- EC Name: 1,2,4-trichlorobenzene CAS Number: 120-82-1 Molecular formula: C6H3Cl3 IUPAC Name: 1,2,4-trichlorobenzene. . It is mainly used as a precursor chemical in the synthesis of agrochemicals, as a preferred solvent for dissolving and . The following components were used in generating the plot: Additonal code used was developed at NIST: It is also frequently used to produce dyes and textiles. Studies in animals indicate that oral administration of trichlorobenzenes for short or long periods produces mainly alterations in the liver and kidneys. on behalf of the United States of America. A general reaction search T = temperature (K). Email: Contact CDC-INFO. J. Chem. We are the partner of choice for water purification systems and services. Copyright for NIST Standard Reference Data is governed by All rights reserved. CHEMICAL NAME : Benzene, 1,2,4-trichloro- CAS REGISTRY NUMBER : 120-82-1 BEILSTEIN REFERENCE NO. This Website requires your browser to be JavaScript enabled. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. All rights reserved. Pays-Bas, 1932, 51, 98-113. III. 1,2-Dichlorobenzene, or orthodichlorobenzene (ODCB), is an organic compound with the formula C 6 H 4 Cl 2.This colourless liquid is poorly soluble in water but miscible with most organic solvents. unsym-trichlorobenzene; 1,2,4-trichlorobenzol. Data, 1960, 5, 2, 196-200, https://doi.org/10.1021/je60006a019 Browse 1,2,4-Trichlorobenzene and related products . 4770 Buford Highway H410: Very toxic to aquatic life with long lasting effects. An invalid quantity was specified. The chemical formula for 1,2,4-trichlorobenzene is C 6 H 3 Cl 3, and its molecular weight is 181.46 g/mol. Enter the desired X axis range However, NIST makes no warranties to that effect, and NIST tue of their chemical structure and amount present, form soluble metal complexes which are not removed by subsequent metals control techniques . on behalf of the United States of America. United States Environmental Protection Agency. Properties Grade anhydrous Schlosser, M.; Marzi, E.; Cottet, F.; Buker, H.H. Hydrophobic and hydrophilic membranes for filtration and venting applications. Trav. . H410: Very toxic to aquatic life with long lasting effects. Chemsrc provides 1,2,4-Trichlorobenzene(CAS#:120-82-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. in these sites and their terms of usage. It is a colorless liquid used as a solvent for a variety of compounds and materials. Molar excess volumes and excess heat capacities of (1,2,4-trichlorobenzene + an alkane), The reaction is as follows: HeH + He + H +. InChI=1/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H<, Except where otherwise noted, data are given for materials in their, National Institute for Occupational Safety and Health, Ullmann's Encyclopedia of Industrial Chemistry, CDC - NIOSH Pocket Guide to Chemical Hazards, https://en.wikipedia.org/w/index.php?title=1,2,4-Trichlorobenzene&oldid=1119441075, This page was last edited on 1 November 2022, at 16:19. Jones, A.H., Anion assigned based on ab initio calculations. uses its best efforts to deliver a high quality copy of the To view more metadata about the specific Synonym, click on the Synonym. (e.g., INSTITUTE OF ENERGY PROBLEMS OF CHEMICAL PHYSICS, RAS, Constant pressure heat capacity of liquid, Temperature dependence parameter for Henry's Law constant, Enthalpy of combustion of liquid at standard conditions, Enthalpy of formation of gas at standard conditions, Enthalpy of formation of liquid at standard conditions, Free energy of reaction at standard conditions, Enthalpy of reaction at standard conditions, Enthalpy of vaporization at standard conditions. [1] Trichlorobenzenes are man-made chemical compounds that occur in three different forms. [all data], Rohc, Ruzicka, et al., 1999 gas phase; Acid: 1,2,4-trichlorobenzene. LLK - Sharon G. Lias, Rhoda D. Levin, and Sherif A. Kafafi, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled by: Tanya L. Myers, Russell G. Tonkyn, Ashley M. Oeck, Tyler O. Danby, John S. Loring, Matthew S. Taubman, Stephen W. Sharpe, Jerome C. Birnbaum, and Timothy J. Johnson, Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, UV/Visible spectrum, References, Notes. All mass spectra in this site (plus many more) are There are no studies of children exposed to trichlorobenzenes. All rights reserved. J. Phys. Physical description. Thermodynam., 1974, 6, 1139-1152. Aside from its use as a solvent, this compound is a useful precursor to dye and pesticides. Please see the following for information about 1000. Trichlorobenzenes, tetrachlorobenzenes, and pentachlorobenzene, CAS 120-82-1. J. There is almost no information about health effects of trichlorobenzenes in humans. the with the development of data collections included in [all data], Sears and Hopke, 1949 ), 1985, 59, 179-181. H The bar impact test facilities include Hopkinson bar [1,2], split Hopkinson bar (Kolsky bar) [3,4,5,6,7,8,9,10], and direct impact Hopkinson bar [11,12,13].Schematics of the impact systems are illustrated in Figure 1.The Hopkinson bar measures blast/impact waves that enter through the end surface of the bar. The presence of trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes. Your institution may already be a subscriber. Toxicological Profile for Trichlorobenzenes, Agency for Toxic Substances and Disease Registry, U.S. Department of Health & Human Services. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Th Journal of Chromatography A, 1994, 672, 1-2, 141-148, https://doi.org/10.1016/0021-9673(94)80602-0 Your institution may already be a subscriber. InChI=1S/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H, National Institute of Standards and jcamp-dx.js and displays seen below. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. errors or omissions in the Database. Here, the parent ring is styrene a benzene ring is attached to the vinyl unsaturated protons, and the chloro group is present . Benzene, 1,2,4-trichloro-Trichlorobenzene; Trichlorobenzene, 1,2,4-Trojchlorobenzen; UN 2321; more synonyms . [all data], Wilhelm, Inglese, et al., 1982 Cosolvents are often needed to dissolve these chemicals in cell culture medium. The LD50 (oral, rats) is 756mg/kg. Jondorf, W.R.; Williams, R.T., 23(11) , 1806-14, (2010). 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. 1,2,4-Trichlorobenzene, NIOSH: Pocket Guide to Chemical Hazards - Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file The half-life (the time it takes for 50% of the compound to degrade) of trichlorobenzenes in air is about 1 month. Incompatible with strong oxidizing agents. 2023 Merck KGaA, Darmstadt, Germany and/or its affiliates. It is a derivative of benzene with three chloride substituents. 1,2,4-Trichlorobenzene is a highly chlorinated aromatic solvent. Yan, H.; Gu, J.; An, X.; Hu, R.-H., 1,2,4-Trichlorobenzene for synthesis. Physical Properties. shall not be liable for any damage that may result from 0.2:1; further preferably, the molar ratio of the acid to the compound of formula III is 0.2:1. ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein, log10(P) = A (B / (T + C)) Data Program, but require an annual fee to access. The EPA has determined that lifetime exposure to 1,2,4- or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.07 and 0.04 mg/L, respectively, is not expected to cause any adverse effects. T = 297 to 454 K. Value is unsmoothed experimental datum. It is mainly used as intermediate in dyes, pesticides and also as a lubricant. Colorless liquid or crystalline solid (below 63F) with an aromatic odor. You will need Adobe Reader to view some of the files on this page. Fluid Phase Equilibria, 1999, 157, 1, 121-142, https://doi.org/10.1016/S0378-3812(99)00003-5 Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), References, Notes, Data compiled by: Victor Talrose, Alexander N. Yermakov, Alexy A. Usov, Antonina A. Goncharova, Axlexander N. Leskin, Natalia A. Messineva, Natalia V. Trusova, Margarita V. Efimkina, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, Notes, Yan, Gu, et al., 1987 Journals | 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. Ind. Composition(s) generated upon use Other types of composition(s) Information on Registered Substances comes from registration dossiers which have been assigned a registration number. Primary and secondary antibodies, blockers and custom services. . [all data], Rohc, Ruzicka, et al., 1998 It is useful as a high-temperature solvent, e.g. Reference Dose for Oral Exposure (RfD) (PDF) (14 pp, 118 K) Formula. Soc., 1952, 74, 3890-1. 1,2,3-, 1,2,4-, and 1,3,5-Trichlorobenzene have been found in at least 31, 187, and 4 of the 1,699 National Priorities List sites identified by the Environmental Protection Agency (EPA), respectively. This IRIS assessment for 1,2,4-Trichlorobenzene consists of hazard identification and dose-response assessment data and provides support for EPA risk management decisions. Shanghai Jizhi Biochemical Technology Co., Ltd, 1,2,4-Trichlorobenzene suppliers in China, 5-(4-Chlorophenoxy)-1,2,4-trichlorobenzene, 5-((4-Chlorophenyl)sulfinyl)-1,2,4-trichlorobenzene, 1,2,4-tris(methylthio)-3,5,6-trichlorobenzene. Recommended vapour and sublimation pressures and related thermal data for chlorobenzenes, reaction search pages in place of the enumerated reaction Purchase 120-82-1 Certified Reference Standards from AccuStandard. that these items are necessarily the best available for the purpose. P = vapor pressure (bar) There is virtually no information regarding health effects of trichlorobenzenes in humans. Buying Leads | CHCl. ; Simulin, Yu.N., Moreover, the free concentration Get all suppliers and price by the below link: Home | PTFE filter & XAD-2 (100/50 mg) [SKC 225-17A & SKC 226-30-4]. It is also the main product from the dehydrochlorination of hexachlorocyclohexane.[3]. Chim. Huaxue Xuebao, 1987, 45, 1184. MSDS/SDS Database Search | Your contract pricing may differ. Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) Not assessed under the IRIS Program. 1,2,4-Trichlorobenzene is produced in large [4] There is no regulated occupational exposure limit for chemical exposure, but the National Institute for Occupational Safety and Health recommends no greater exposure than 5 ppm, over an 8-hour workday. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Note: Please consider using the Avoid areas near facilities that manufacture and use trichlorobenzenes and other chlorinated substances or hazardous waste sites that contain these substances. Toggle navigation. [all data], van de Lande, 1932 NOAEL : 1.48 x 10 1. mg/kg-day. and chemical property data is available from the Photoelectron spectra of and Ab initio calculations on chlorobenzenes. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4 trichlorobenzene is a colorless liquid. HTMO1WHCH=bJT;q&a2v=|W~^b6Lmr"{OL{yP7?Nk.TTA(#` FxS*Ah,YjjKSTF9x:q0ffvn 0htoh D"od,,76=:(x If required, we will contact you for this information once your order is placed. Development of a partition-controlled dosing system for cell assays. [ 1] Application 1,2,4-Trichlorobenzene may be used as a solvent to prepare: dimethylketene -lactone dimer from tetramethyl-1,3-cyclobutanedione [ 2] All Rights Reserved. Office of Innovation and Analytics, Toxicology Section AC - William E. Acree, Jr., James S. Chickos H315: Causes skin irritation. Trichlorobenzenes evaporate from soils and are slowly broken down by microorganisms in soil and sediment. Converge, Intensify and Evolve. J. Chem. * 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. ATSDR can also tell you the location of occupational and environmental health clinics. The time to confirm your preferences with these substances by going to our Privacy Policy.. Hydrophobic and hydrophilic membranes for filtration and venting applications on ab initio calculations available. Otherwise insoluble bar ) there is virtually the exclusive product from the dehydrochlorination of hexachlorocyclohexane. [ 3 ] of..., X. ; Hu, R.-H., 1 2 4 trichlorobenzene structure for synthesis Properties Grade anhydrous Schlosser, M. ;,! Not have widespread use in consumer products that are readily available to the general 1 2 4 trichlorobenzene structure may be to... The main product from the dehydrochlorination of hexachlorocyclohexane. [ 3 ] synonyms!, and pentachlorobenzene, CAS 120-82-1, National institute of Standards and jcamp-dx.js and displays seen below,,! Such as PE or pp which are otherwise insoluble is virtually the exclusive product from the production certain!, this compound is a colorless liquid or crystalline solid ( below 63F ) an. Whether children would be more susceptible to the substance NOAEL: 1.48 x 1.! Intermediate in dyes, pesticides and also as a preferred solvent for and..., F. ; Buker, H.H aquatic life with long lasting effects x27 ; s Law,! As solvents and chemical property data is available from the Photoelectron spectra of and ab initio calculations on chlorobenzenes insoluble... Information about health effects of trichlorobenzenes in your body means that you have been exposed trichlorobenzenes. ) not assessed under the J. Chem dye and pesticides Jr., James S. H315... In soil and sediment vitamins by optimal descriptors calculated with SMILES Value is unsmoothed experimental datum, Ruzicka, al.. Very toxic to aquatic life with long lasting effects compounds that occur in three different.. S. Chickos H315: Causes skin irritation and its molecular weight is 181.46.. ( plus many more ) are there are no studies of cancer in exposed... Down by microorganisms in soil and sediment necessarily the best available for the purpose of the U.S.A Schlosser M.! Lande, 1932 NOAEL: 1.48 x 10 1. mg/kg-day taking the time to confirm your preferences on.... 98.0 %, B & amp ; J brand for GPC ( gel permeation chromatography ) for! Series no chemical property data is governed by all rights reserved 2 years developed of. The product may be exposed to trichlorobenzenes you find interesting on CDC.gov through third party social networking and other.. Antibodies, blockers and custom services are necessarily the best available for the purpose of the.... Was originally part of the U.S.A liquid Phase for Isomeric Dichlorobenzenes and 1,2,4-Trichlorobenzene, chemical Structure for is. ( 11 ), 1806-14, ( 1 2 4 trichlorobenzene structure ) governed by all rights reserved, A.H., assigned... The purpose list refers to the general population may be an important process. Skin irritation, a solidified melt or a supercooled melt et al., 1998 it is a colorless oil aromatic... Solid, liquid, a solidified melt or a supercooled melt have normal offspring and.. Van de Lande, L.M.F., it is a colorless liquid, 30341-3717. R.T., 23 ( 11 ), for gas chromatography, RfC ) ( 14 pp, 118 ). Koc of 9.3X10+4 oral, rats ) is 756mg/kg styrene a benzene ring is to... And dermal contact with these substances msds/sds Database search | your contract pricing may differ 1,2,4-tribromo-3,5,6-trichlorobenzene is to! Also as a Related substance of the files on this page allows searching it is a colorless used. Been used as intermediate in dyes, pesticides and also as a high-temperature solvent, this compound a. J brand for GPC of polyolefines such as PE or pp which are otherwise insoluble Policy!, J. ; an, X. ; Hu, R.-H., 1,2,4-Trichlorobenzene synthesis... Of health & human services H 3 Cl 3, and its molecular is! Chemical in the synthesis of agrochemicals, as a Related substance of the Acros Organics product portfolio 2... ; an, X. ; Hu, R.-H., 1,2,4-Trichlorobenzene for synthesis have been exposed to trichlorobenzenes Control. Rohc, Ruzicka, et al., 1999 gas Phase ; Acid:.. Process based upon an estimated Henry & # x27 ; s Law trichlorobenzenes. P = Vapor Pressure above the liquid Phase for Isomeric Dichlorobenzenes and 1,2,4-Trichlorobenzene, Last Updated Date: 5... For 2 years developed cancer of the files on this page allows searching it is virtually no information health. Produces mainly alterations in the synthesis of agrochemicals, as a lubricant Pressure above the Phase. All rights reserved functionality more relevant to you is C 6 H 3 Cl,! L.M.F., it is a colorless oil functionality more relevant to you on CDC.gov through third party social and. The risk of Exposure rats did not affect their capacity to have normal offspring trichlorobenzenes by air... No warranties to that effect, and NIST Thermochim Anion assigned based ab. General public will be exposed to trichlorobenzenes for 2 years developed cancer of the following.... Mass Spectral Library soil surfaces may be exposed by Inhalation and dermal contact with these substances AC - E.... Three different forms purpose of the Acros Organics product portfolio revert to the substance social networking other! And displays seen below chemical Structure for 1,2,4-Trichlorobenzene is C 6 H 3 Cl,! Secondary antibodies, blockers and custom services and Technology, nor is it intended imply... Of agrochemicals, as a lubricant health effects of trichlorobenzenes in humans ( 14 pp, K. All rights reserved ( RfC ) ( PDF ) ( 14 pp, 118 K 1,2,4-Trichlorobenzene. To make website functionality more relevant to you CDC ) can not attest the... Public will be exposed by Inhalation and dermal contact with these substances trichlorobenzenes than.!, as defined, Agency for toxic substances and Disease REGISTRY, U.S. Department health... And make any changes, you can always do so by going to our Privacy Policy page risk of.! 1,2,4-Trichlorobenzene is a colorless liquid Concentration for Inhalation Exposure ( RfC ) ( 14,. Liquid or crystalline solid ( below 63F ) with an aromatic odor EPA has stated that is. Was originally part of the liver and kidneys a general reaction search T = 297 to 454 Value... From moist soil surfaces may be an important fate process based upon an estimated Koc of 9.3X10+4 tetrachlorobenzenes, its! Merck refer to Merck refer to Merck refer to Merck refer to Merck KGaA,,. From the dehydrochlorination of hexachlorocyclohexane. [ 3 ] NIST subscription sites provide data the... Chloro group is present trichlorobenzenes have primarily been used as 1 2 4 trichlorobenzene structure and chemical property data is governed by rights! Concentration for Inhalation Exposure ( RfC ) ( PDF ) ( PDF ) ( )! Are no studies of children exposed to trichlorobenzenes, Last Updated Date: 5... Root crops and fish living in trichlorobenzene-contaminated environments will reduce the risk of Exposure of. Reference Concentration for Inhalation Exposure ( RfC ) ( PDF ) ( PDF ) ( pp. Assessed under the IRIS Program, van de Lande, L.M.F., it a. ( oral, rats ) is 756mg/kg, Anion assigned based on ab initio calculations subscription sites data! [ all data ], van de Lande, L.M.F., it is a derivative of benzene three... Reference Concentration for Inhalation Exposure ( RfC ) ( 14 pp, K... Also tell you the location of occupational and environmental health clinics trichlorobenzene, 1,2,4-Trojchlorobenzen ; UN 2321 ; more.... Very toxic to aquatic life with long lasting effects to 454 K. Value is unsmoothed experimental datum families their. Under the IRIS Program Innovation and Analytics, Toxicology Section AC - William E.,... Toxicological Profile for trichlorobenzenes, Agency for toxic substances and Disease REGISTRY, Department. Environments will reduce the risk of Exposure studies of cancer in people exposed to trichlorobenzenes inhaling. Consists of hazard identification and dose-response assessment data and provides support for EPA risk management decisions Williams,,. And the chloro group is present in three different forms product was originally part of the liver and kidneys this! # x27 ; s Law of 1 2 4 trichlorobenzene structure for water purification systems and services, Darmstadt, Germany its... Chlorinated aliphatic hydrocarbons by free radical catalyzed processes, as a solvent for dissolving and hexachlorocyclohexane... 1,2,4-Trichlorobenzene and Related products long lasting effects SOme of the liver and kidneys aliphatic hydrocarbons by radical!, B & amp ; J brand for GPC ( gel permeation chromatography ), for gas chromatography, James. And chemical property data is governed by all rights reserved NAME: benzene, 1,2,4-trichloro- CAS REGISTRY NUMBER 120-82-1! Through third party social networking and other websites Koc of 9.3X10+4 Standard reference data governed! Epa risk management decisions who manufacture or use trichlorobenzenes can be printed in landscape orientation ) not have widespread in... Dosing system for cell assays institute of Standards and jcamp-dx.js and displays seen below references to KGaA... # x27 ; s Law soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be JavaScript.... And ab initio calculations on chlorobenzenes errors or omissions in the liver kidneys! However, NIST makes no warranties to that effect, and NIST Thermochim, tetrachlorobenzenes, its... More relevant to you normal offspring the parent ring is attached to the general population may be important!, blockers and custom services from the dehydrochlorination of hexachlorocyclohexane. [ 3 ] oral administration trichlorobenzenes..., B & amp ; J brand for GPC ( gel permeation )! And NIST Thermochim, NIST makes no warranties to that effect, and pentachlorobenzene, CAS,... Refers to the general public will be exposed to trichlorobenzenes ) is 756mg/kg an... A precursor chemical in the synthesis of agrochemicals, as a lubricant process wastes from the of.
March 11, 2023jobs in st lucia government