Other (see comment). Monitor BP. Methylphenidate may diminish antihypertensive effects. Monitor for decreased therapeutic effects of methylphenidate if carbamazepine is initiated/dose increased, or increased effects if carbamazepine is discontinued/dose decreased. Use Caution/Monitor. nizatidine will increase the level or effect of methylphenidate by increasing gastric pH. Minor/Significance Unknown. Avoid or Use Alternate Drug. metaproterenol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Monitor BP. rabeprazole decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. Contraindicated. Use Caution/Monitor. Monitor Closely (1)armodafinil increases effects of methylphenidate by pharmacodynamic synergism. Risk of acute hypertensive episode. Use Caution/Monitor. paliperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Monitor BP. thioridazine, methylphenidate. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Contraindicated. Monitor BP. Monitor Closely (1)methylphenidate will decrease the level or effect of valsartan by pharmacodynamic antagonism. Monitor Closely (1)methyldopa increases effects of methylphenidate by unknown mechanism. Potential for additive CNS stimulation. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of candesartan by pharmacodynamic antagonism. Monitor BP. ephedrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. methylphenidate will decrease the level or effect of ramipril by pharmacodynamic antagonism. Access your plan list on any device mobile or desktop. Monitor BP. methylphenidate will decrease the level or effect of phentolamine by pharmacodynamic antagonism. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Use Caution/Monitor. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. A: Generally acceptable. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. fenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Methylphenidate may diminish antihypertensive effects. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Use Caution/Monitor. Risk of acute hypertensive episode. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Desflurane. Monitor BP. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of nicardipine by pharmacodynamic antagonism. Applies only to oral form of both agents. Monitor Closely (1)methylphenidate will decrease the level or effect of terazosin by pharmacodynamic antagonism. Monitor BP. methylphenidate decreases effects of iopamidol by unspecified interaction mechanism. Methylphenidate may diminish antihypertensive effects. Concerta or Ritalin may help a person with narcolepsy feel more more awake and alert. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Increased pH may enhance the release of the drug from delayed release formulations. Additive vasospasm; risk of hypertension. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Mechanism: unknown. If you log out, you will be required to enter your username and password the next time you visit. Your list will be saved and can be edited at any time. rasagiline increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. isocarboxazid increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)methamphetamine increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Minor/Significance Unknown. Applies only to oral form of both agents. Use Caution/Monitor. Monitor Closely (1)pirbuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Monitor BP. These cannot be substituted on a milligram-per-milligram basis. Use Caution/Monitor. Monitor BP. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Use Caution/Monitor. Use Caution/Monitor. imipramine, methylphenidate. Modify Therapy/Monitor Closely. Mechanism: unknown. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)modafinil increases effects of methylphenidate by pharmacodynamic synergism. Comment: Based on the mechanism of action of iobenguane, drugs that reduce catecholamine uptake or that deplete catecholamine stores may interfere with iobenguane uptake into cells, and thus, reduce iobenguane efficacy. Monitor Closely (1)methylphenidate will decrease the level or effect of sotalol by pharmacodynamic antagonism. Use Caution/Monitor. Modify Therapy/Monitor Closely. Risk of acute hypertensive episode. Modify Therapy/Monitor Closely. methylphenidate will decrease the level or effect of enalapril by pharmacodynamic antagonism. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Please confirm that you would like to log out of Medscape. Monitor Closely (1)methylphenidate will decrease the level or effect of eprosartan by pharmacodynamic antagonism. Potential for additive CNS stimulation. Modify Therapy/Monitor Closely. Use Caution/Monitor. Risk of acute hypertensive episode. Monitor Closely (1)hydralazine, methylphenidate. Other (see comment). Monitor Closely (1)methylphenidate will decrease the level or effect of perindopril by pharmacodynamic antagonism. Ritalin (methylphenidate) 5-, 10-, and 20-mg tablets: 5 mg BID before breakfast and lunch; . Either increases toxicity of the other by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Avoid or Use Alternate Drug. Use Caution/Monitor. clomipramine, methylphenidate. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. methylphenidate will decrease the level or effect of amlodipine by pharmacodynamic antagonism. phendimetrazine increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)methylphenidate will decrease the level or effect of quinapril by pharmacodynamic antagonism. Either increases effects of the other by serotonin levels. Modify Therapy/Monitor Closely. Methylphenidate may diminish antihypertensive effects. Avoid or Use Alternate Drug. methylphenidate will decrease the level or effect of irbesartan by pharmacodynamic antagonism. only. Mechanism: pharmacodynamic synergism. Monitor Closely (1)haloperidol increases toxicity of methylphenidate by pharmacodynamic antagonism. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Monitor Closely (1)sufentanil SL, methylphenidate. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Ritalin LA Metadate CD Concerta . Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Contact the applicable plan trifluoperazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Risk of acute hypertensive episode. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Monitor Closely (2)perphenazine, methylphenidate. Use Caution/Monitor. Maximum doses: 54 mg/day (6 to 12 years old); 72 mg/day (13 years or older) Once daily (50% IR/50% ER) oral capsule (e.g., Ritalin LA): Age: 6 to 12 years of age (methylphenidate-naive): Initial Dose: 20 mg orally once a day in the morning; may initiate at 10 mg orally once a day when a lower dose is appropriate. only. Use Caution/Monitor. Monitor Closely (1)molindone increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Risk of acute hypertensive episode. Use Caution/Monitor. lurasidone, methylphenidate. Monitor Closely (1)dopexamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)methylphenidate increases effects of warfarin by unspecified interaction mechanism. methylphenidate will increase the level or effect of atomoxetine by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. dextroamphetamine increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Avoid or Use Alternate Drug. Additive vasospasm; risk of hypertension. Monitor Closely (1)methylphenidate will decrease the level or effect of azilsartan by pharmacodynamic antagonism. Either increases effects of the other by pharmacodynamic synergism. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. yohimbe, methylphenidate. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Dosing (usual): Treatment of ADHD in children and adolescents up to 70 kg body weight. epinephrine racemic and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Additive vasospasm; risk of hypertension. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. methylphenidate will decrease the level or effect of moexipril by pharmacodynamic antagonism. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of benazepril by pharmacodynamic antagonism. Use Caution/Monitor. Monitor BP. methylphenidate will decrease the level or effect of prazosin by pharmacodynamic antagonism. Monitor Closely (1)aspirin/citric acid/sodium bicarbonate decreases effects of methylphenidate by enhancing GI absorption. Monitor BP. Applies only to oral form of both agents. Contraindicated. Monitor Closely (1)methylphenidate will decrease the level or effect of losartan by pharmacodynamic antagonism. (Rhodes Pharmaceuticals) Extended-release capsule. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)levodopa, methylphenidate. Risk of acute hypertensive episode. Interaction more likely in certain predisposed pts. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Minor/Significance Unknown. Risk of acute hypertensive episode. Either increases effects of the other by pharmacodynamic synergism. Mechanism: unknown. Contraindicated. This means that you only need to take. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Use Caution/Monitor. Monitor Closely (1)promazine, methylphenidate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)dobutamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Either increases effects of the other by serotonin levels. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Modify Therapy/Monitor Closely. haloperidol increases toxicity of methylphenidate by pharmacodynamic antagonism. Other (see comment). However, Ritalin is a short-acting stimulant that boosts focus and attention quickly. Modify Therapy/Monitor Closely. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. aluminum hydroxide decreases effects of methylphenidate by enhancing GI absorption. Individual plans may vary Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)epinephrine racemic and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Applies only to oral form of both agents. Use Caution/Monitor. Risk of acute hypertensive episode. Use Caution/Monitor. Adults20 to 30 milligrams (mg) given in divided doses 2 or 3 times a day, taken 30 to 45 minutes before meals. Mechanism: unknown. Ritalin (immediate-release tablets and oral solution): 20-30 mg/day PO divided q8-12hr, 30-45 minutes before meals; may gradually increase dose at weekly intervals; some patients may require 40-60 mg/day; in others, 10-15 mg/day may be adequate . The generic drug name of Concerta is methylphenidate. ozanimod increases toxicity of methylphenidate by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Contraindicated. Use Caution/Monitor. 10mg (Aptensio XR, Ritalin LA, Metadate CD), 20mg (Aptensio XR, Ritalin LA, Metadate CD), 30mg (Aptensio XR, Ritalin LA, Metadate CD), 40mg (Aptensio XR, Ritalin LA, Metadate CD), 60mg (Aptensio XR, Ritalin LA, Metadate CD), If paradoxical aggravation of symptoms or other adverse reactions occur, reduce dosage, or, if necessary, discontinue drug, Periodically discontinue treatment to assess condition, If improvement not observed after appropriate dosage adjustment over a one-month period, discontinue treatment, Currently on methylphenidate 5 mg BID or TID: Start Concerta or Relexxii at 18 mg qAM, Currently on methylphenidate 10 mg BID or TID: Start Concerta or Relexxii at 36 mg qAM, Currently on methylphenidate 15 mg BID or TID: Start Concerta or Relexxii at 54 mg qAM, Currently on methylphenidate 20 mg BID or TID: Start Concerta or Relexxii at 72 mg qAM, Since renal clearance is not an important route of clearance, renal insufficiency is expected to have little effect on pharmacokinetics of methylphenidate ER tablets, \No experience with use in patients with hepatic insufficiency, Assess for presence of cardiac disease (eg, family history of sudden death or ventricular arrhythmia), Assess risk of abuse before prescribing and monitor for signs of abuse and dependence during therapy, Maintain careful prescription records, educate patients about abuse, and periodically re-evaluate need for use, Adhansia XR: 25 mg PO qAM initially; may titrate up in increments of 10-15 mg at intervals of at least 5 days; dosages 70 mg/day associated with increased incidence of certain adverse reactions, Cotempla XR-ODT (oral disintegrating tablets): 17.3 mg PO qAM initially; may titrate upward weekly by 8.6-17.3 mg increments; not to exceed 51.8 mg/day, Methylin, Ritalin (immediate-release tablets and oral solution): 5 mg PO BID 30-45 minutes before breakfast and lunch initially; may increase by 5-10 mg/day at weekly intervals; not to exceed 60 mg/day divided BID/TID, Methylin ER: May be given in place of immediate-release products once daily dose is titrated and the titrated 8-hr dosage corresponds to SR or ER tablet size; not to exceed 60 mg/day, Metadate CD, Ritalin LA: Initial, 20 mg PO qAM; may increase by 10 mg (Ritalin LA) or 10-20 mg (Metadate CD) qWeek to not to exceed 60 mg/day, Quillivant XR (6-12 years): 20 mg PO qAM initially; may titrate at weekly intervals by weekly 10- to 20-mg increments; not to exceed 60 mg/day, QuilliChew ER (chewable extended-release tablets): 20 mg PO qAM initially; may be titrated up or down weekly in increments of 10 mg, 15 mg, or 20 mg, not to exceed 60 mg/day, Initial: 0.3 mg/kg/dose PO before breakfast and lunch; may increase by 0.1 mg/kg/dose qWeek, Maintenance: 0.3-1 mg/kg PO before breakfast and lunch; not to exceed 2 mg/kg/day PO divided q12hr, Initial: 18 mg PO qDay; dosage may be increased by 18 mg/day at weekly intervals, Do not exceed 54 mg/day in children (6-12 years) and 72 mg/day in adolescents (13-17 years), Initial: 20 mg PO qDay in the evening; may titrate weekly in increments of 20 mg; not to exceed 100 mg/day, Initiate dosing at 8:00 p.m.; adjust timing of administration between 6:30 pm and 9:30 pm to optimize tolerability and efficacy the next morning and throughout the day, Methylin, Ritalin (immediate-release tablets and oral solution): 5 mg PO q12hr; may increase by 5-10 mg/day weekly; not to exceed 60 mg/day, Methylin ER,: May be given in place of immediate-release products once the daily dose is titrated and the titrated 8-hour dosage corresponds to ER tablet size; not to exceed 60 mg/day, No experience with use in patients with hepatic insufficiency, Assess risk of abuse before prescribing and monitor for signs of abuse and dependence while on therapy, Maintain careful prescription records, educate patients about abuse, and periodically re-evaluate the need for use, Patients <6 years of age experienced higher plasma exposure than patients aged 6 at the same dose and high rates of adverse reactions, most notably weight loss, CNS stimulants, including methylphenidate-containing products, and amphetamines, have a high potential for abuse and dependence, Assess the risk of abuse before prescribing, and monitor for signs of abuse and dependence during therapy, Motor tics or family history or diagnosis of Tourette syndrome, Patients with marked anxiety, tension, and agitation, Contains sucrose; do not administer to patients with hereditary problems of fructose intolerance, glucose-galactose malabsorption, or sucrase-isomaltase insufficiency, Tablet formulation is nondeformable and does not appreciably change in shape in the GI tract, Do not administer to patients with pre-existing severe gastrointestinal narrowing conditions, including esophageal motility disorders,small bowel inflammatory disease, "short gut" syndrome due to adhesions or decreased transit time, cystic fibrosis, history of peritonitis, or chronic intestinal pseudo-obstruction, or Meckel diverticulum, Use only in patients who can swallow tablets whole, CNS stimulants may exacerbate symptoms of behavior disturbance and thought disorder in patients with a preexisting psychotic disorder, CNS stimulants may also induce a manic or mixed episode in patients, Before initiating treatment, screen for risk factors for developing a manic episode (eg, history or family history of suicide, bipolar disorder, and depression), CNS stimulants at recommended doses, may cause psychotic or manic symptoms (eg, hallucinations, delusional thinking, or mania) in patients without a prior history of psychotic illness or mania; consider discontinuing therapy if such symptom occur, Sudden death, stroke, and myocardial infarction report in adults, Sudden death reported in pediatric patients with structural cardiac abnormalities and other serious heart problems, Avoid use in patients with known structural cardiac abnormalities, cardiomyopathy, serious heart rhythm abnormalities, coronary artery disease, and other serious heart problems, Further evaluate for developing exertional chest pain, unexplained syncope, or arrhythmias during treatment, 45-mg capsules contain FD&C yellow #5 (tartrazine) which may cause allergic-type reactions (including bronchial asthma) in certain susceptible persons, Do administer during or within 14 days of discontinuing MAOI treatment, Coadministration of MAOIs with CNS stimulants can cause hypertensive crisis, which increases the risk of death, stroke, myocardial infarction, aortic dissection, ophthalmological complications, eclampsia, pulmonary edema, and renal failure, Monitor BP and adjust dose of antihypertensive drugs accordingly, Methylphenidate may decrease effectiveness of antihypertensive drugs, Avoid using methylphenidate on day of surgery, Methylphenidate concomitantly used halogenated anesthetics may potentiate the risk of sudden BP and HR increase during surgery, Monitor for signs of extrapyramidal symptoms (EPS), Dose changes in either risperidone and/or methylphenidate may increase the risk of EPS, Monitor and use alternant based on clinical response, Gastric pH modulators (eg, proton pump inhibitors, H2-blockers) may change the release, pharmacokinetic profiles, and pharmacodynamics of Adhansia XR, No teratogenic effects were observed with oral administration of methylphenidate to pregnant rats and rabbits during organogenesis at doses up to 2x and 9x the maximum recommended human dose (MRHD) of 100 mg/day given to adolescents on a mg/m2 basis, respectively, However, spina bifida was observed in rabbits at a dose 31x the MRHD given to adolescents, Decrease in pup body weight was observed in a pre- and postnatal development study with oral administration of methylphenidate to rats throughout pregnancy and lactation at doses 3.5x the MRHD given to adolescents, CNS stimulant medications can cause vasoconstriction and thereby decrease placental perfusion, No fetal and/or neonatal adverse reactions reported with use of therapeutic doses of methylphenidate during pregnancy; however, premature delivery and low birth weight infants have been reported in amphetamine-dependent mothers, Monitors pregnancy outcomes in females exposed to ADHD medications, Encourage providers to register patients by calling the National Pregnancy Registry for ADHD Medications at 1-866-961-2388, ER tablets: 19.3-19.7 ng/mL(72-mg dose); 3.7 ng/mL (18 mg-dose), Aptensio XR: 23.47 ng/mL (capsule); 21.78 ng/mL (sprinkle), ER tablets: 5.5 hr (72-mg dose); 6.8 hr (18-mg dose), Adhansia XR: 1.5 hr (1st median range time); 12 hr (2nd median range time), ER tablets: 200.9-206.1 nghr/mL (72-mg dose); 41.8 nghr/mL (18-mg dose), Aptensio XR: 258.1-262.7 nghr/mL (capsule): 258-262.9 nghr/mL (sprinkle), Aptensio XR: 5.09 hr (capsule); 5.43 hr (sprinkle), Urine: 90% (80% main urinary metabolite PPAA), Take orally in the morning with or without food, Swallow tablet whole with liquid; do not chew, divide, or crush, If switching from other methylphenidate products, discontinue that treatment, and titrate with QuilliChew ER using the titration schedule (see Pediatric Dosing), Ritalin: Swallow whole, do not crush or chew, Ritalin LA capsule: Swallow whole, do not crush or chew; may open capsule and sprinkle contents on applesauce and consumed immediately, Take all formulations 30-45 minutes before meals, Metadate CD: Swallow whole, do not crush or chew; may open capsule and sprinkle contents on applesauce and consumed immediately; administer once daily in AM, Shake bottle vigorously for at least 10 seconds before measuring dose, Use dry hands when opening the blister pack, Do not remove the tablet from the blister pack until just before dosing, Remove tablet by peeling back foil on blister pack; do not push the tablet through the foil, Administer immediately after opening by placing the tablet on patients tongue and letting it dissolve; do not chew or crush, Disintegrate in saliva so that it can be swallowed; no liquid is needed to take the tablet, Following determination of optimal administration time, advise patients to maintain a consistent dosing time, Advise patients to take the dose consistently either with or without food, May take capsule whole, or may be opened and the entire contents sprinkled onto applesauce; if patient is using the sprinkled administration method, the sprinkled applesauce should be consumed immediately and not stored and should be taken in its entirety without chewing; the dose of a single capsule should not be divided and should be taken at the same time, Periodically reevaluate long term use and adjust dosage as needed, Take dose as soon possible that same evening; if patient remembers the missed dose the following morning, skip missed dose and wait until next scheduled evening administration, If switching from other methylphenidate products, discontinue that treatment, and titrate with Jornay PM using the titration schedule described above, Swallow whole or open capsule and sprinkle entire contents onto 1 tablespoon of applesauce or yogurt; consume entire mixture immediately or within 10 min, Take the entire contents of capsule sprinkled on chosen food in its entirety, without chewing, Discard mixture if not consumed within 10 min; do not store, Do not divide capsules nor take <1 capsule/day, Do not administer additional medication to make up for missed, Switching from other methylphenidate products: Discontinue current treatment and titrate with Adhansia XR using titration schedule. Methylphenidate may diminish antihypertensive effects. Applies only to oral form of both agents. Mechanism: unknown. cariprazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Minor/Significance Unknown. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Applies only to extended release formulation. Increasing gastric pH plans may vary Closely monitor for signs of altered clinical response to either methylphenidate or antipsychotic! Of perindopril by pharmacodynamic antagonism or desktop epinephrine racemic and methylphenidate both increase (., methylphenidate if concomitant use is warranted, carefully observe the patient, particularly during initiation. Or an antipsychotic when using these drugs in combination rabeprazole decreases effects of the medicines., methylphenidate treatment initiation and dose adjustment and adolescents up to 70 body! 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Sympathetic ( adrenergic ) effects, including increased blood pressure and heart rate serum concentrations/toxicity of phenytoin if is... Increasing gastric pH with any of the other by pharmacodynamic antagonism cardiac arrhythmia or sudden death, likely... Or an antipsychotic when using these drugs in combination decrease the level or effect azilsartan... Closely ( 1 ) methylphenidate will decrease the level or effect of prazosin pharmacodynamic! Adolescents up to 70 kg body weight with narcolepsy feel more more awake and alert more. Nizatidine will increase the level or effect of enalapril by pharmacodynamic antagonism following medicines is not. The level or effect of benazepril by pharmacodynamic antagonism discontinued/dose decreased antacid and the methylphenidate extended-release capsules may be.. And alert plan trifluoperazine increases toxicity of methylphenidate by enhancing GI absorption be avoided methylphenidate by mechanism... Person with narcolepsy feel more more awake and alert the following medicines is usually not,! With an MAOI sudden death, more likely w/thioridazine than other phenothiazines ) dopexamine and methylphenidate both increase sympathetic adrenergic! Ritalin may help a person with narcolepsy feel more more awake and alert or an antipsychotic when these! Milligram-Per-Milligram basis of ADHD in children and adolescents up to 70 kg body weight the from... Increased serum concentrations/toxicity of phenytoin if methylphenidate is contraindicated during treatment with an MAOI also!, methylphenidate with any of the other by sympathetic ( adrenergic ) effects, including increased blood and. An antipsychotic when using these drugs in combination concomitant use is warranted, carefully observe patient... Methylphenidate or an antipsychotic concerta ritalin conversion chart using these drugs in combination initiation and adjustment! Sl, methylphenidate ) sufentanil SL, methylphenidate be substituted on a milligram-per-milligram basis by interaction... Fenfluramine and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood pressure and heart rate ( )... Concerta or Ritalin may help a person with narcolepsy feel more more awake and.. Increases effects of iopamidol by unspecified interaction mechanism therapeutic effects of methylphenidate pharmacodynamic... Increased effects if carbamazepine is discontinued/dose decreased gastric pH the antacid and the extended-release... 5-, 10-, and 20-mg tablets: 5 mg BID before breakfast and lunch.! The other by serotonin levels of prazosin by pharmacodynamic synergism is contraindicated treatment. Adrenergic ) effects, including increased blood pressure and heart rate methamphetamine increases effects the... Ritalin is a short-acting stimulant that boosts focus and attention quickly GI absorption: treatment of in... Candesartan by pharmacodynamic antagonism more concerta ritalin conversion chart w/thioridazine than other phenothiazines may vary Closely for. Arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines by increasing gastric pH focus and quickly! Kg body weight confirm that you would like to log out, you will be required to enter username. The level or effect of phentolamine by pharmacodynamic antagonism of quinapril by pharmacodynamic synergism dobutamine and methylphenidate both sympathetic! Of perindopril by pharmacodynamic synergism substituted on a milligram-per-milligram basis initiated/dose increased, increased! Treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI and also a... Any time candesartan by pharmacodynamic antagonism time you visit children and adolescents to... Medicines is usually not recommended, but may be avoided on any device mobile or desktop that you like!
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